Divergent mechanisms of steroid inhibition in the human ρ1 GABA A receptor
Divergent mechanisms of steroid inhibition in the human ρ1 GABA A receptor
About this item
Full title
Author / Creator
Publisher
England
Journal title
Language
English
Formats
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Publisher
England
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Scope and Contents
Contents
ρ-type γ-aminobutyric acid-A (GABA
) receptors are widely distributed in the retina and brain, and are potential drug targets for the treatment of visual, sleep and cognitive disorders. Endogenous neuroactive steroids including β-estradiol and pregnenolone sulfate negatively modulate the function of ρ1 GABA
receptors, but their inhibitory mec...
Alternative Titles
Full title
Divergent mechanisms of steroid inhibition in the human ρ1 GABA A receptor
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_kth_353440
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_kth_353440
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-51904-7
