Polymorphisms in CARD8 and NLRP3 are associated with extrapulmonary TB and poor clinical outcome in...
Polymorphisms in CARD8 and NLRP3 are associated with extrapulmonary TB and poor clinical outcome in active TB in Ethiopia
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Full title
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Innate immunity is a first line defense against
Mycobacterium tuberculosis
infection where inflammasome activation and secretion of the pro-inflammatory cytokine IL-1beta, plays a major role. Thus, genetic polymorphisms in innate immunity-related genes such as CARD8 and NLRP3 may contribute to the understanding of why most exposed individuals...
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Full title
Polymorphisms in CARD8 and NLRP3 are associated with extrapulmonary TB and poor clinical outcome in active TB in Ethiopia
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TN_cdi_swepub_primary_oai_DiVA_org_liu_155568
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_liu_155568
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-40121-8
