A poor metabolizer of both CYP2C19 and CYP2D6 identified by mechanistic pharmacokinetic simulation i...
A poor metabolizer of both CYP2C19 and CYP2D6 identified by mechanistic pharmacokinetic simulation in a fatal drug poisoning case involving venlafaxine
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Author / Creator
Jornil, J , Nielsen, T.S , Rosendal, I , Ahlner, J , Zackrisson, A.L , Boel, L.W.T and Brock, B
Publisher
Ireland: Elsevier Ireland Ltd
Journal title
Language
English
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Publication information
Publisher
Ireland: Elsevier Ireland Ltd
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Scope and Contents
Contents
Abstract We present a fatal drug poisoning case involving venlafaxine (VEN). The deceased took his medication regularly (including 150 mg VEN twice daily), and nothing in the case or autopsy findings pointed towards suicide. The toxicological assessment concluded that the cause of death was most likely due to a poisoning with a combination of VEN,...
Alternative Titles
Full title
A poor metabolizer of both CYP2C19 and CYP2D6 identified by mechanistic pharmacokinetic simulation in a fatal drug poisoning case involving venlafaxine
Authors, Artists and Contributors
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_liu_91940
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_liu_91940
Other Identifiers
ISSN
0379-0738,1872-6283
E-ISSN
1872-6283
DOI
10.1016/j.forsciint.2012.12.020