The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structur...
The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Dynamic interactions of proteins with lipid membranes are essential regulatory events in biology, but remain rudimentarily understood and particularly overlooked in membrane proteins. The ubiquitously expressed membrane protein Na
+
/H
+
-exchanger 1 (NHE1) regulates intracellular pH (pH
i
) with dysregulation linked to e.g. cance...
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Full title
The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity
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TN_cdi_swepub_primary_oai_DiVA_org_mau_37152
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_mau_37152
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-020-01455-6