Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells
Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by type-II alveolar epithelial cell (AECII) injury and fibroblast hyperproliferation. Severe AECII endoplasmic reticulum (ER) stress is thought to underlie IPF, but is yet incompletely understood. We studied the regulation of C/EBP homologous protein (CHOP), a proapoptotic ER-stre...
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Full title
Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells
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TN_cdi_swepub_primary_oai_DiVA_org_su_170827
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_su_170827
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ISSN
0946-2716,1432-1440
E-ISSN
1432-1440
DOI
10.1007/s00109-019-01787-9