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Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells

Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_su_170827

Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells

About this item

Full title

Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Journal of molecular medicine (Berlin, Germany), 2019-07, Vol.97 (7), p.973-990

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by type-II alveolar epithelial cell (AECII) injury and fibroblast hyperproliferation. Severe AECII endoplasmic reticulum (ER) stress is thought to underlie IPF, but is yet incompletely understood. We studied the regulation of C/EBP homologous protein (CHOP), a proapoptotic ER-stre...

Alternative Titles

Full title

Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_su_170827

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_su_170827

Other Identifiers

ISSN

0946-2716,1432-1440

E-ISSN

1432-1440

DOI

10.1007/s00109-019-01787-9

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