β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insu...
β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion
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Publisher
United States: American Diabetes Association
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Language
English
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Publisher
United States: American Diabetes Association
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Contents
The role of uncoupling protein 2 (UCP2) in pancreatic β-cells is highly debated, partly because of the broad tissue distribution of UCP2 and thus limitations of whole-body UCP2 knockout mouse models. To investigate the function of UCP2 in the β-cell, β-cell-specific UCP2 knockout mice (UCP2BKO) were generated and characterized.
UCP2BKO mice were...
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Full title
β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion
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TN_cdi_swepub_primary_oai_DiVA_org_su_70903
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_su_70903
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ISSN
0012-1797,1939-327X
E-ISSN
1939-327X
DOI
10.2337/db11-0132