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β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insu...

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_su_70903

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion

About this item

Full title

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion

Publisher

United States: American Diabetes Association

Journal title

Diabetes (New York, N.Y.), 2011-11, Vol.60 (11), p.2710-2719

Language

English

Formats

Publication information

Publisher

United States: American Diabetes Association

More information

Scope and Contents

Contents

The role of uncoupling protein 2 (UCP2) in pancreatic β-cells is highly debated, partly because of the broad tissue distribution of UCP2 and thus limitations of whole-body UCP2 knockout mouse models. To investigate the function of UCP2 in the β-cell, β-cell-specific UCP2 knockout mice (UCP2BKO) were generated and characterized.
UCP2BKO mice were...

Alternative Titles

Full title

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_su_70903

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_su_70903

Other Identifiers

ISSN

0012-1797,1939-327X

E-ISSN

1939-327X

DOI

10.2337/db11-0132

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