Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: Potential mechanism for uremic va...
Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: Potential mechanism for uremic vascular calcification
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Pyrophosphate is a potent inhibitor of medial vascular calcification where its level is controlled by hydrolysis via a tissue-nonspecific alkaline phosphatase (TNAP). We sought to determine if increased TNAP activity could explain the pyrophosphate deficiency and vascular calcification seen in renal failure. TNAP activity increased twofold in intac...
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Full title
Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: Potential mechanism for uremic vascular calcification
Authors, Artists and Contributors
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_umu_11528
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_11528
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ISSN
0085-2538,1523-1755
E-ISSN
1523-1755
DOI
10.1038/ki.2008.26
