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Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_152398

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

About this item

Full title

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-09, Vol.8 (1), p.14223-13, Article 14223

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Aggregation of mutant superoxide dismutase 1 (SOD1) is a pathological hallmark of a subset of familial ALS patients. However, the possible role of misfolded wild type SOD1 in human ALS is highly debated. To ascertain whether or not misfolded SOD1 is a common pathological feature in non-
SOD1
ALS, we performed a blinded histological and bioche...

Alternative Titles

Full title

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_umu_152398

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_152398

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-31773-z

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