Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive...
Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation
About this item
Full title
Author / Creator
Proserpio, Valentina , Piccolo, Andrea , Haim-Vilmovsky, Liora , Kar, Gozde , Lönnberg, Tapio , Svensson, Valentine , Pramanik, Jhuma , Natarajan, Kedar Nath , Zhai, Weichao , Zhang, Xiuwei , Donati, Giacomo , Kayikci, Melis , Kotar, Jurij , McKenzie, Andrew N. J. , Montandon, Ruddy , Billker, Oliver , Woodhouse, Steven , Cicuta, Pietro , Nicodemi, Mario and Teichmann, Sarah A.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Differentiation of lymphocytes is frequently accompanied by cell cycle changes, interplay that is of central importance for immunity but is still incompletely understood. Here, we interrogate and quantitatively model how proliferation is linked to differentiation in CD4+ T cells.
We perform ex vivo single-cell RNA-sequencing of CD4+ T cells duri...
Alternative Titles
Full title
Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation
Authors, Artists and Contributors
Author / Creator
Piccolo, Andrea
Haim-Vilmovsky, Liora
Kar, Gozde
Lönnberg, Tapio
Svensson, Valentine
Pramanik, Jhuma
Natarajan, Kedar Nath
Zhai, Weichao
Zhang, Xiuwei
Donati, Giacomo
Kayikci, Melis
Kotar, Jurij
McKenzie, Andrew N. J.
Montandon, Ruddy
Billker, Oliver
Woodhouse, Steven
Cicuta, Pietro
Nicodemi, Mario
Teichmann, Sarah A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_umu_165847
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_165847
Other Identifiers
ISSN
1474-760X,1474-7596,1465-6906
E-ISSN
1474-760X
DOI
10.1186/s13059-016-0957-5
