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DNA methylation changes and increased mRNA expression of coagulation proteins, factor V and thrombom...

DNA methylation changes and increased mRNA expression of coagulation proteins, factor V and thrombom...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_200178

DNA methylation changes and increased mRNA expression of coagulation proteins, factor V and thrombomodulin in Fuchs endothelial corneal dystrophy

About this item

Full title

DNA methylation changes and increased mRNA expression of coagulation proteins, factor V and thrombomodulin in Fuchs endothelial corneal dystrophy

Journal title

Cellular and molecular life sciences : CMLS, 2023, Vol.80 (3)

Language

English

Formats

Subjects

More information

Scope and Contents

Contents

Late-onset Fuchs endothelial corneal dystrophy (FECD) is a disease affecting the corneal endothelium (CE), associated with a cytosine-thymine-guanine repeat expansion at the CTG18.1 locus in the transcription factor 4 (TCF4) gene. It is unknown whether CTG18.1 expansions affect global methylation including TCF4 gene in CE or whether global CE methy...

Alternative Titles

Full title

DNA methylation changes and increased mRNA expression of coagulation proteins, factor V and thrombomodulin in Fuchs endothelial corneal dystrophy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_umu_200178

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_200178

Other Identifiers

ISSN

1420-9071,1420-682X

DOI

10.21203/rs.3.rs-1758860/v1

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