Improved Measurement of Drug Exposure in the Brain Using Drug-Specific Correction for Residual Blood
Improved Measurement of Drug Exposure in the Brain Using Drug-Specific Correction for Residual Blood
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Publisher
London, England: SAGE Publications
Journal title
Language
English
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Publisher
London, England: SAGE Publications
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Scope and Contents
Contents
A major challenge associated with the determination of the unbound brain-to-plasma concentration ratio of a drug (Kp,uu,brain), is the error associated with correction for the drug in various vascular spaces of the brain, i.e., in residual blood. The apparent brain vascular spaces of plasma water (Vwater, 10.3 μL/g brain), plasma proteins (Vprotein...
Alternative Titles
Full title
Improved Measurement of Drug Exposure in the Brain Using Drug-Specific Correction for Residual Blood
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_uu_123010
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_123010
Other Identifiers
ISSN
0271-678X,1559-7016
E-ISSN
1559-7016
DOI
10.1038/jcbfm.2009.200
