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Modeling of In Vitro Drug Activity and Prediction of Clinical Outcome in Acute Myeloid Leukemia

Modeling of In Vitro Drug Activity and Prediction of Clinical Outcome in Acute Myeloid Leukemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_13509

Modeling of In Vitro Drug Activity and Prediction of Clinical Outcome in Acute Myeloid Leukemia

About this item

Full title

Modeling of In Vitro Drug Activity and Prediction of Clinical Outcome in Acute Myeloid Leukemia

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

Journal of clinical pharmacology, 2007-08, Vol.47 (8), p.1014-1021

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

The objectives of this study were to develop a population pharmacodynamic model describing the in vitro drug sensitivity of tumor cells and to relate in vitro parameters to clinical outcome. Cell samples from 179 patients with acute myelocytic leukemia were exposed to cytosine arabinoside and daunorubicin, and cytotoxicity was analyzed using the fl...

Alternative Titles

Full title

Modeling of In Vitro Drug Activity and Prediction of Clinical Outcome in Acute Myeloid Leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_13509

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_13509

Other Identifiers

ISSN

0091-2700,1552-4604

E-ISSN

1552-4604

DOI

10.1177/0091270007302563

How to access this item