Modeling of In Vitro Drug Activity and Prediction of Clinical Outcome in Acute Myeloid Leukemia
Modeling of In Vitro Drug Activity and Prediction of Clinical Outcome in Acute Myeloid Leukemia
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Language
English
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Contents
The objectives of this study were to develop a population pharmacodynamic model describing the in vitro drug sensitivity of tumor cells and to relate in vitro parameters to clinical outcome. Cell samples from 179 patients with acute myelocytic leukemia were exposed to cytosine arabinoside and daunorubicin, and cytotoxicity was analyzed using the fl...
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Modeling of In Vitro Drug Activity and Prediction of Clinical Outcome in Acute Myeloid Leukemia
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TN_cdi_swepub_primary_oai_DiVA_org_uu_13509
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_13509
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ISSN
0091-2700,1552-4604
E-ISSN
1552-4604
DOI
10.1177/0091270007302563