The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines
The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines
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Publisher
Dordrecht: Springer Netherlands
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Language
English
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Publisher
Dordrecht: Springer Netherlands
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Scope and Contents
Contents
In response to ionizing radiation, several signaling cascades in the cell are activated to repair the DNA breaks, prevent apoptosis, and keep the cells proliferating. AKT is important for survival and proliferation and may also be an activating factor for DNA-PKcs and MRE11, which are essential proteins in the DNA repair process. AKT (PKB) is hyper...
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Full title
The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_uu_221446
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_221446
Other Identifiers
ISSN
1010-4283,1423-0380
E-ISSN
1423-0380
DOI
10.1007/s13277-013-1465-9