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The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines

The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_221446

The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines

About this item

Full title

The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines

Publisher

Dordrecht: Springer Netherlands

Journal title

Tumor biology, 2014-04, Vol.35 (4), p.3525-3534

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

In response to ionizing radiation, several signaling cascades in the cell are activated to repair the DNA breaks, prevent apoptosis, and keep the cells proliferating. AKT is important for survival and proliferation and may also be an activating factor for DNA-PKcs and MRE11, which are essential proteins in the DNA repair process. AKT (PKB) is hyper...

Alternative Titles

Full title

The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_221446

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_221446

Other Identifiers

ISSN

1010-4283,1423-0380

E-ISSN

1423-0380

DOI

10.1007/s13277-013-1465-9

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