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The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_232994

The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

About this item

Full title

The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2014-09, Vol.124 (9), p.3975-3986

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

In glaucoma, aqueous outflow into the Schlemm's canal (SC) is obstructed. Despite striking structural and functional similarities with the lymphatic vascular system, it is unknown whether the SC is a blood or lymphatic vessel. Here, we demonstrated the expression of lymphatic endothelial cell markers by the SC in murine and zebrafish models as well...

Alternative Titles

Full title

The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_232994

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_232994

Other Identifiers

ISSN

0021-9738,1558-8238

E-ISSN

1558-8238

DOI

10.1172/JCI75395

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