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U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cel...

U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_245563

U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cells

About this item

Full title

U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cells

Publisher

United States: John Wiley & Sons, Inc

Journal title

Cancer medicine (Malden, MA), 2014-08, Vol.3 (4), p.812-824

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

It is well known that in vitro subculture represents a selection pressure on cell lines, and over time this may result in a genetic drift in the cancer cells. In addition, long‐term cultures harbor the risk of cross‐contamination with other cell lines. The consequences may have major impact on experimental results obtained in various laboratories,...

Alternative Titles

Full title

U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_245563

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_245563

Other Identifiers

ISSN

2045-7634

E-ISSN

2045-7634

DOI

10.1002/cam4.219

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