U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cel...
U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cells
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United States: John Wiley & Sons, Inc
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English
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United States: John Wiley & Sons, Inc
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Contents
It is well known that in vitro subculture represents a selection pressure on cell lines, and over time this may result in a genetic drift in the cancer cells. In addition, long‐term cultures harbor the risk of cross‐contamination with other cell lines. The consequences may have major impact on experimental results obtained in various laboratories,...
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U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cells
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TN_cdi_swepub_primary_oai_DiVA_org_uu_245563
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_245563
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ISSN
2045-7634
E-ISSN
2045-7634
DOI
10.1002/cam4.219