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Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_359993

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

About this item

Full title

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2018-07, Vol.136 (1), p.41-56

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

The gradual deterioration of cognitive functions in Alzheimer’s disease is paralleled by a hierarchical progression of amyloid-beta and tau brain pathology. Recent findings indicate that toxic oligomers of amyloid-beta may cause propagation of pathology in a prion-like manner, although the underlying mechanisms are incompletely understood. Here we...

Alternative Titles

Full title

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_359993

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_359993

Other Identifiers

ISSN

0001-6322,1432-0533

E-ISSN

1432-0533

DOI

10.1007/s00401-018-1868-1