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Reduced dose folinic acid rescue after rapid high-dose methotrexate clearance is not associated with...

Reduced dose folinic acid rescue after rapid high-dose methotrexate clearance is not associated with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_469027

Reduced dose folinic acid rescue after rapid high-dose methotrexate clearance is not associated with increased toxicity in a pediatric cohort

About this item

Full title

Reduced dose folinic acid rescue after rapid high-dose methotrexate clearance is not associated with increased toxicity in a pediatric cohort

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Supportive care in cancer, 2022-01, Vol.30 (1), p.127-133

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Low doses of folinic acid (FA) rescue after high-dose methotrexate (HD-MTX) have been associated with increased toxicity, whereas high doses may be related to a decreased antileukemic effect. The optimal dosage and duration of FA rescue remain controversial. This study was designed to investigate, whether a shorter duration of FA rescue...

Alternative Titles

Full title

Reduced dose folinic acid rescue after rapid high-dose methotrexate clearance is not associated with increased toxicity in a pediatric cohort

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_469027

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_469027

Other Identifiers

ISSN

0941-4355,1433-7339

E-ISSN

1433-7339

DOI

10.1007/s00520-021-06395-3

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