Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice
Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Mucin-type O-linked oligosaccharides (O-glycans) are primary components of the intestinal mucins that form the mucus gel layer overlying the gut epithelium. Impaired expression of intestinal O-glycans has been observed in patients with ulcerative colitis (UC), but its role in the etiology of this disease is unknown. Here, we report that mice with i...
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Full title
Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice
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Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_142061
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_142061
Other Identifiers
ISSN
0021-9738,1558-8238
E-ISSN
1558-8238
DOI
10.1172/JCI45538
