Nasal and skin delivery of IC31 ®-adjuvanted recombinant HSV-2 gD protein confers protection against...
Nasal and skin delivery of IC31 ®-adjuvanted recombinant HSV-2 gD protein confers protection against genital herpes
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Publisher
Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Contents
Highlights► Immunization of mice with gD plus IC31 ® elicits serum antibodies with HSV-2 neutralizing activity. ► Skin and nasomucosal immunization induce gD-specific antibodies in vaginas of mice immunized with IC31 ®-adjuvanted gD. ► Intradermal immunization with gD plus IC31 ® induces strong splenic lymphoproliferative and IFN-γ responses. ► Imm...
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Full title
Nasal and skin delivery of IC31 ®-adjuvanted recombinant HSV-2 gD protein confers protection against genital herpes
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Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_158664
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_158664
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2012.02.019