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Nasal and skin delivery of IC31 ®-adjuvanted recombinant HSV-2 gD protein confers protection against...

Nasal and skin delivery of IC31 ®-adjuvanted recombinant HSV-2 gD protein confers protection against...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_158664

Nasal and skin delivery of IC31 ®-adjuvanted recombinant HSV-2 gD protein confers protection against genital herpes

About this item

Full title

Nasal and skin delivery of IC31 ®-adjuvanted recombinant HSV-2 gD protein confers protection against genital herpes

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2012-06, Vol.30 (29), p.4361-4368

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights► Immunization of mice with gD plus IC31 ® elicits serum antibodies with HSV-2 neutralizing activity. ► Skin and nasomucosal immunization induce gD-specific antibodies in vaginas of mice immunized with IC31 ®-adjuvanted gD. ► Intradermal immunization with gD plus IC31 ® induces strong splenic lymphoproliferative and IFN-γ responses. ► Imm...

Alternative Titles

Full title

Nasal and skin delivery of IC31 ®-adjuvanted recombinant HSV-2 gD protein confers protection against genital herpes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_gup_ub_gu_se_158664

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_158664

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2012.02.019

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