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Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_231696

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

About this item

Full title

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

Publisher

England: BioMed Central Ltd

Journal title

Molecular neurodegeneration, 2016-01, Vol.11 (1), p.3-3, Article 3

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The discovery that heterozygous missense mutations in the gene encoding triggering receptor expressed on myeloid cells 2 (TREM2) are risk factors for Alzheimer's disease (AD), with only the apolipoprotein E (APOE) ε4 gene allele conferring a higher risk, has led to increased interest in immune biology in the brain. TREM2 is expressed on microglia,...

Alternative Titles

Full title

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_gup_ub_gu_se_231696

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_231696

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/s13024-016-0071-x

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