Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
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England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Contents
The discovery that heterozygous missense mutations in the gene encoding triggering receptor expressed on myeloid cells 2 (TREM2) are risk factors for Alzheimer's disease (AD), with only the apolipoprotein E (APOE) ε4 gene allele conferring a higher risk, has led to increased interest in immune biology in the brain. TREM2 is expressed on microglia,...
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Full title
Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
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TN_cdi_swepub_primary_oai_gup_ub_gu_se_231696
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_231696
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-016-0071-x