Amyloid precursor protein expression and processing are differentially regulated during cortical neu...
Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation
About this item
Full title
Author / Creator
Bergström, Petra , Agholme, Lotta , Nazir, Faisal Hayat , Satir, Tugce Munise , Toombs, Jamie , Wellington, Henrietta , Strandberg, Joakim , Bontell, Thomas Olsson , Kvartsberg, Hlin , Holmström, Maria , Boreström, Cecilia , Simonsson, Stina , Kunath, Tilo , Lindahl, Anders , Blennow, Kaj , Hanse, Eric , Portelius, Erik , Wray, Selina and Zetterberg, Henrik
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Amyloid precursor protein (APP) and its cleavage product amyloid β (Aβ) have been thoroughly studied in Alzheimer’s disease. However, APP also appears to be important for neuronal development. Differentiation of induced pluripotent stem cells (iPSCs) towards cortical neurons enables
in vitro
mechanistic studies on human neuronal development....
Alternative Titles
Full title
Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation
Authors, Artists and Contributors
Author / Creator
Agholme, Lotta
Nazir, Faisal Hayat
Satir, Tugce Munise
Toombs, Jamie
Wellington, Henrietta
Strandberg, Joakim
Bontell, Thomas Olsson
Kvartsberg, Hlin
Holmström, Maria
Boreström, Cecilia
Simonsson, Stina
Kunath, Tilo
Lindahl, Anders
Blennow, Kaj
Hanse, Eric
Portelius, Erik
Wray, Selina
Zetterberg, Henrik
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_239627
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_239627
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep29200
