AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent...
AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Aims/hypothesis
In this study, we aimed to evaluate the therapeutic potential of 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), an activator of AMP-activated protein kinase, for ameliorating high-fat diet (HFD)-induced pathophysiology in mice. We also aimed to determine whether the beneficial effects of AICAR were dependent on adiponecti...
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Full title
AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin
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Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_251842
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_251842
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ISSN
0012-186X,1432-0428
E-ISSN
1432-0428
DOI
10.1007/s00125-017-4211-9