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AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent...

AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_251842

AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin

About this item

Full title

AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Diabetologia, 2017-04, Vol.60 (4), p.729-739

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Aims/hypothesis
In this study, we aimed to evaluate the therapeutic potential of 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), an activator of AMP-activated protein kinase, for ameliorating high-fat diet (HFD)-induced pathophysiology in mice. We also aimed to determine whether the beneficial effects of AICAR were dependent on adiponecti...

Alternative Titles

Full title

AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_gup_ub_gu_se_251842

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_251842

Other Identifiers

ISSN

0012-186X,1432-0428

E-ISSN

1432-0428

DOI

10.1007/s00125-017-4211-9

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