Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia mai...
Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy
About this item
Full title
Author / Creator
the Nordic Society of Paediatric Haematology and Oncology (NOPHO) , Nordic Society of Paediatric Haematology and Oncology (NOPHO) , Nersting, Jacob , Nielsen, Stine Nygaard , Grell, Kathrine , Paerregaard, Maria , Abrahamsson, Jonas , Lund, Bendik , Jonsson, Olafur Gisli , Pruunsild, Kaie , Vaitkeviciene, Goda , Kanerva, Jukka and Schmiegelow, Kjeld
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Purpose
Methotrexate polyglutamates (MTXpg) facilitate incorporation of thioguanine nucleotides into DNA (DNA-TG, the primary cytotoxic thiopurine metabolite and outcome determinant in MTX/6-mercaptopurine treatment of childhood ALL). We hypothesized that mapping erythrocyte levels of MTXpg with 1–6 glutamates and their associations with DNA-TG...
Alternative Titles
Full title
Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy
Authors, Artists and Contributors
Author / Creator
Nordic Society of Paediatric Haematology and Oncology (NOPHO)
Nersting, Jacob
Nielsen, Stine Nygaard
Grell, Kathrine
Paerregaard, Maria
Abrahamsson, Jonas
Lund, Bendik
Jonsson, Olafur Gisli
Pruunsild, Kaie
Vaitkeviciene, Goda
Kanerva, Jukka
Schmiegelow, Kjeld
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_275265
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_275265
Other Identifiers
ISSN
0344-5704,1432-0843
E-ISSN
1432-0843
DOI
10.1007/s00280-018-3704-7
