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Repotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma cells

Repotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_287999

Repotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma cells

About this item

Full title

Repotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-12, Vol.9 (1), p.19353-12, Article 19353

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Neuroblastoma is the most commonly diagnosed extracranial tumor in the first year of life. Approximately 9% of neuroblastoma patients present germline or somatic aberrations in the gene encoding for anaplastic lymphoma kinase (ALK). This increases in high-risk neuroblastomas, which have a 14% frequency of
ALK
aberrations at the time of diagno...

Alternative Titles

Full title

Repotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_gup_ub_gu_se_287999

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_287999

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-55060-7

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