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The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1

The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_338274

The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1

About this item

Full title

The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2024-05, Vol.390 (20), p.1873-1884

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

Subjects

Subjects and topics

More information

Scope and Contents

Contents

In this study, interferon-γ was found to play a large role in the pathogenesis of APS-1. Results were confirmed in studies in animals and led to a trial of ruxolitinib in five patients, who had dramatic responses.

Alternative Titles

Full title

The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_gup_ub_gu_se_338274

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_338274

Other Identifiers

ISSN

0028-4793,1533-4406

E-ISSN

1533-4406

DOI

10.1056/NEJMoa2312665