The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1
The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1
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Author / Creator
Oikonomou, Vasileios , Smith, Grace , Constantine, Gregory M. , Schmitt, Monica M. , Ferré, Elise M.N. , Alejo, Julie C. , Riley, Deanna , Kumar, Dhaneshwar , Dos Santos Dias, Lucas , Pechacek, Joseph , Hadjiyannis, Yannis , Webb, Taura , Seifert, Bryce A. , Ghosh, Rajarshi , Walkiewicz, Magdalena , Martin, Daniel , Besnard, Marine , Snarr, Brendan D. , Deljookorani, Shiva , Lee, Chyi-chia R. , DiMaggio, Tom , Barber, Princess , Rosen, Lindsey B. , Cheng, Aristine , Rastegar, Andre , de Jesus, Adriana A. , Stoddard, Jennifer , Kuehn, Hye Sun , Break, Timothy J. , Kong, Heidi H. , Castelo-Soccio, Leslie , Colton, Ben , Warner, Blake M. , Kleiner, David E. , Quezado, Martha M. , Davis, Jeremy L. , Fennelly, Kevin P. , Olivier, Kenneth N. , Rosenzweig, Sergio D. , Suffredini, Anthony F. , Anderson, Mark S. , Swidergall, Marc , Guillonneau, Carole , Notarangelo, Luigi D. , Goldbach-Mansky, Raphaela , Neth, Olaf , Monserrat-Garcia, Maria Teresa , Valverde-Fernandez, Justo , Lucena, Jose Manuel , Gomez-Gila, Ana Lucia , Garcia Rojas, Angela , Seppänen, Mikko R. J. , Lohi, Jouko , Hero, Matti , Laakso, Saila , Klemetti, Paula , Lundberg, Vanja , Ekwall, Olov , Olbrich, Peter , Winer, Karen K. , Afzali, Behdad , Moutsopoulos, Niki M. , Holland, Steven M. , Heller, Theo , Pittaluga, Stefania and Lionakis, Michail S.
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
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Publication information
Publisher
United States: Massachusetts Medical Society
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More information
Scope and Contents
Contents
In this study, interferon-γ was found to play a large role in the pathogenesis of APS-1. Results were confirmed in studies in animals and led to a trial of ruxolitinib in five patients, who had dramatic responses.
Alternative Titles
Full title
The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1
Authors, Artists and Contributors
Author / Creator
Smith, Grace
Constantine, Gregory M.
Schmitt, Monica M.
Ferré, Elise M.N.
Alejo, Julie C.
Riley, Deanna
Kumar, Dhaneshwar
Dos Santos Dias, Lucas
Pechacek, Joseph
Hadjiyannis, Yannis
Webb, Taura
Seifert, Bryce A.
Ghosh, Rajarshi
Walkiewicz, Magdalena
Martin, Daniel
Besnard, Marine
Snarr, Brendan D.
Deljookorani, Shiva
Lee, Chyi-chia R.
DiMaggio, Tom
Barber, Princess
Rosen, Lindsey B.
Cheng, Aristine
Rastegar, Andre
de Jesus, Adriana A.
Stoddard, Jennifer
Kuehn, Hye Sun
Break, Timothy J.
Kong, Heidi H.
Castelo-Soccio, Leslie
Colton, Ben
Warner, Blake M.
Kleiner, David E.
Quezado, Martha M.
Davis, Jeremy L.
Fennelly, Kevin P.
Olivier, Kenneth N.
Rosenzweig, Sergio D.
Suffredini, Anthony F.
Anderson, Mark S.
Swidergall, Marc
Guillonneau, Carole
Notarangelo, Luigi D.
Goldbach-Mansky, Raphaela
Neth, Olaf
Monserrat-Garcia, Maria Teresa
Valverde-Fernandez, Justo
Lucena, Jose Manuel
Gomez-Gila, Ana Lucia
Garcia Rojas, Angela
Seppänen, Mikko R. J.
Lohi, Jouko
Hero, Matti
Laakso, Saila
Klemetti, Paula
Lundberg, Vanja
Ekwall, Olov
Olbrich, Peter
Winer, Karen K.
Afzali, Behdad
Moutsopoulos, Niki M.
Holland, Steven M.
Heller, Theo
Pittaluga, Stefania
Lionakis, Michail S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_338274
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_338274
Other Identifiers
ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2312665