SLCO1B1 Variants and Statin-Induced Myopathy — A Genomewide Study
SLCO1B1 Variants and Statin-Induced Myopathy — A Genomewide Study
About this item
Full title
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Publisher
Boston, MA: Massachusetts Medical Society
Journal title
Language
English
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Publication information
Publisher
Boston, MA: Massachusetts Medical Society
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Scope and Contents
Contents
A genomewide screen of patients with myopathy who were taking high-dose simvastatin (80 mg per day) showed a strong association between myopathy and variants of
SLCO1B1,
which encodes an organic anion–transporting polypeptide. Approximately 60% of the cases of myopathy could be attributed to these variants. The association was replicated in a...
Alternative Titles
Full title
SLCO1B1 Variants and Statin-Induced Myopathy — A Genomewide Study
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Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_91314
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_91314
Other Identifiers
ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMoa0801936
