Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolutio...
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution
About this item
Full title
Author / Creator
Rodriguez-Meira, Alba , Norfo, Ruggiero , Wen, Sean , Chédeville, Agathe L. , Rahman, Haseeb , O’Sullivan, Jennifer , Wang, Guanlin , Louka, Eleni , Kretzschmar, Warren W. , Paterson, Aimee , Brierley, Charlotte , Martin, Jean-Edouard , Demeule, Caroline , Bashton, Matthew , Sousos, Nikolaos , Moralli, Daniela , Subha Meem, Lamia , Carrelha, Joana , Wu, Bishan , Hamblin, Angela , Guermouche, Helene , Pasquier, Florence , Marzac, Christophe , Girodon, François , Vainchenker, William , Drummond, Mark , Harrison, Claire , Chapman, J. Ross , Plo, Isabelle , Jacobsen, Sten Eirik W. , Psaila, Bethan , Thongjuea, Supat , Antony-Debré, Iléana and Mead, Adam J.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Understanding the genetic and nongenetic determinants of tumor protein 53 (
TP53
)
-
mutation-driven clonal evolution and subsequent transformation is a crucial step toward the design of rational therapeutic strategies. Here we carry out allelic resolution single-cell multi-omic analysis of hematopoietic stem/progenitor cells (HSPCs) fr...
Alternative Titles
Full title
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution
Authors, Artists and Contributors
Author / Creator
Norfo, Ruggiero
Wen, Sean
Chédeville, Agathe L.
Rahman, Haseeb
O’Sullivan, Jennifer
Wang, Guanlin
Louka, Eleni
Kretzschmar, Warren W.
Paterson, Aimee
Brierley, Charlotte
Martin, Jean-Edouard
Demeule, Caroline
Bashton, Matthew
Sousos, Nikolaos
Moralli, Daniela
Subha Meem, Lamia
Carrelha, Joana
Wu, Bishan
Hamblin, Angela
Guermouche, Helene
Pasquier, Florence
Marzac, Christophe
Girodon, François
Vainchenker, William
Drummond, Mark
Harrison, Claire
Chapman, J. Ross
Plo, Isabelle
Jacobsen, Sten Eirik W.
Psaila, Bethan
Thongjuea, Supat
Antony-Debré, Iléana
Mead, Adam J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_444972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_444972
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-023-01480-1
