Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients With...
Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients With Recurrent Glioblastoma: A Randomized Clinical Trial
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Author / Creator
Werlenius, Katja , Kinhult, Sara , Solheim, Tora Skeidsvoll , Magelssen, Henriette , Löfgren, David , Mudaisi, Munila , Hylin, Sofia , Bartek, Jiri , Strandéus, Michael , Lindskog, Magnus , Rashid, Havyan Bahroz , Carstam, Louise , Gulati, Sasha , Solheim, Ole , Bartek, Jiri , Salvesen, Øyvind and Jakola, Asgeir Store
Publisher
United States: American Medical Association
Journal title
Language
English
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Publication information
Publisher
United States: American Medical Association
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Scope and Contents
Contents
Disulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma.
To evaluate the efficacy and safety of disulfiram and copper as add-on to alkylating chemotherapy in patients with recurrent glioblastoma.
This was a multicenter, open-label, randomized pha...
Alternative Titles
Full title
Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients With Recurrent Glioblastoma: A Randomized Clinical Trial
Authors, Artists and Contributors
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_446763
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_446763
Other Identifiers
ISSN
2574-3805
E-ISSN
2574-3805
DOI
10.1001/jamanetworkopen.2023.4149
