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Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arth...

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arth...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_449788

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

About this item

Full title

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

Author / Creator

The BioBank Japan Project , BioBank Japan Project , Ishigaki, Kazuyoshi , Sakaue, Saori , Terao, Chikashi , Luo, Yang , Sonehara, Kyuto , Yamaguchi, Kensuke , Amariuta, Tiffany , Too, Chun Lai , Laufer, Vincent A. , Scott, Ian C. , Viatte, Sebastien , Takahashi, Meiko , Ohmura, Koichiro , Murasawa, Akira , Hashimoto, Motomu , Ito, Hiromu , Hammoudeh, Mohammed , Emadi, Samar Al , Masri, Basel K. , Halabi, Hussein , Badsha, Humeira , Uthman, Imad W. , Wu, Xin , Lin, Li , Li, Ting , Plant, Darren , Barton, Anne , Orozco, Gisela , Verstappen, Suzanne M. M. , Bowes, John , MacGregor, Alexander J. , Honda, Suguru , Koido, Masaru , Tomizuka, Kohei , Kamatani, Yoichiro , Tanaka, Hiroaki , Tanaka, Eiichi , Suzuki, Akari , Maeda, Yuichi , Yamamoto, Kenichi , Miyawaki, Satoru , Xie, Gang , Zhang, Jinyi , Amos, Christopher I. , Keystone, Edward , Wolbink, Gertjan , van der Horst-Bruinsma, Irene , Cui, Jing , Liao, Katherine P. , Carroll, Robert J. , Lee, Hye-Soon , Bang, So-Young , Siminovitch, Katherine A. , de Vries, Niek , Alfredsson, Lars , Rantapää-Dahlqvist, Solbritt , Karlson, Elizabeth W. , Bae, Sang-Cheol , Kimberly, Robert P. , Edberg, Jeffrey C. , Mariette, Xavier , Huizinga, Tom , Dieudé, Philippe , Schneider, Matthias , Kerick, Martin , Denny, Joshua C. , Matsuda, Koichi , Matsuo, Keitaro , Mimori, Tsuneyo , Matsuda, Fumihiko , Fujio, Keishi , Tanaka, Yoshiya , Kumanogoh, Atsushi , Traylor, Matthew , Lewis, Cathryn M. , Eyre, Stephen , Xu, Huji , Saxena, Richa , Arayssi, Thurayya , Kochi, Yuta , Ikari, Katsunori , Harigai, Masayoshi , Gregersen, Peter K. , Yamamoto, Kazuhiko , Louis Bridges, S. , Padyukov, Leonid , Martin, Javier , Klareskog, Lars , Okada, Yukinori and Raychaudhuri, Soumya

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2022-11, Vol.54 (11), p.1640-1651

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Rheumatoid arthritis (RA) is a highly heritable complex disease with unknown etiology. Multi-ancestry genetic research of RA promises to improve power to detect genetic signals, fine-mapping resolution and performances of polygenic risk scores (PRS). Here, we present a large-scale genome-wide association study (GWAS) of RA, which includes 276,020 s...

Alternative Titles

Full title

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

Authors, Artists and Contributors

Author / Creator

The BioBank Japan Project
BioBank Japan Project
Ishigaki, Kazuyoshi
Sakaue, Saori
Terao, Chikashi
Luo, Yang
Sonehara, Kyuto
Yamaguchi, Kensuke
Amariuta, Tiffany
Too, Chun Lai
Laufer, Vincent A.
Scott, Ian C.
Viatte, Sebastien
Takahashi, Meiko
Ohmura, Koichiro
Murasawa, Akira
Hashimoto, Motomu
Ito, Hiromu
Hammoudeh, Mohammed
Emadi, Samar Al
Masri, Basel K.
Halabi, Hussein
Badsha, Humeira
Uthman, Imad W.
Wu, Xin
Lin, Li
Li, Ting
Plant, Darren
Barton, Anne
Orozco, Gisela
Verstappen, Suzanne M. M.
Bowes, John
MacGregor, Alexander J.
Honda, Suguru
Koido, Masaru
Tomizuka, Kohei
Kamatani, Yoichiro
Tanaka, Hiroaki
Tanaka, Eiichi
Suzuki, Akari
Maeda, Yuichi
Yamamoto, Kenichi
Miyawaki, Satoru
Xie, Gang
Zhang, Jinyi
Amos, Christopher I.
Keystone, Edward
Wolbink, Gertjan
van der Horst-Bruinsma, Irene
Cui, Jing
Liao, Katherine P.
Carroll, Robert J.
Lee, Hye-Soon
Bang, So-Young
Siminovitch, Katherine A.
de Vries, Niek
Alfredsson, Lars
Rantapää-Dahlqvist, Solbritt
Karlson, Elizabeth W.
Bae, Sang-Cheol
Kimberly, Robert P.
Edberg, Jeffrey C.
Mariette, Xavier
Huizinga, Tom
Dieudé, Philippe
Schneider, Matthias
Kerick, Martin
Denny, Joshua C.
Matsuda, Koichi
Matsuo, Keitaro
Mimori, Tsuneyo
Matsuda, Fumihiko
Fujio, Keishi
Tanaka, Yoshiya
Kumanogoh, Atsushi
Traylor, Matthew
Lewis, Cathryn M.
Eyre, Stephen
Xu, Huji
Saxena, Richa
Arayssi, Thurayya
Kochi, Yuta
Ikari, Katsunori
Harigai, Masayoshi
Gregersen, Peter K.
Yamamoto, Kazuhiko
Louis Bridges, S.
Padyukov, Leonid
Martin, Javier
Klareskog, Lars
Okada, Yukinori
Raychaudhuri, Soumya

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_449788

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_449788

Other Identifiers

ISSN

1061-4036,1546-1718

E-ISSN

1546-1718

DOI

10.1038/s41588-022-01213-w