Polygenic prediction of educational attainment within and between families from genome-wide associat...
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
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Author / Creator
23andMe Research Team , Social Science Genetic Association Consortium , LifeLines Cohort Study , Okbay, Aysu , Wu, Yeda , Wang, Nancy , Jayashankar, Hariharan , Bennett, Michael , Nehzati, Seyed Moeen , Sidorenko, Julia , Kweon, Hyeokmoon , Goldman, Grant , Gjorgjieva, Tamara , Jiang, Yunxuan , Hicks, Barry , Tian, Chao , Hinds, David A. , Ahlskog, Rafael , Magnusson, Patrik K. E. , Oskarsson, Sven , Hayward, Caroline , Campbell, Archie , Porteous, David J. , Freese, Jeremy , Herd, Pamela , Watson, Chelsea , Jala, Jonathan , Conley, Dalton , Koellinger, Philipp D. , Johannesson, Magnus , Laibson, David , Meyer, Michelle N. , Lee, James J. , Kong, Augustine , Yengo, Loic , Cesarini, David , Turley, Patrick , Visscher, Peter M. , Beauchamp, Jonathan P. , Benjamin, Daniel J. and Young, Alexander I.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk predi...
Alternative Titles
Full title
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Authors, Artists and Contributors
Author / Creator
Social Science Genetic Association Consortium
LifeLines Cohort Study
Okbay, Aysu
Wu, Yeda
Wang, Nancy
Jayashankar, Hariharan
Bennett, Michael
Nehzati, Seyed Moeen
Sidorenko, Julia
Kweon, Hyeokmoon
Goldman, Grant
Gjorgjieva, Tamara
Jiang, Yunxuan
Hicks, Barry
Tian, Chao
Hinds, David A.
Ahlskog, Rafael
Magnusson, Patrik K. E.
Oskarsson, Sven
Hayward, Caroline
Campbell, Archie
Porteous, David J.
Freese, Jeremy
Herd, Pamela
Watson, Chelsea
Jala, Jonathan
Conley, Dalton
Koellinger, Philipp D.
Johannesson, Magnus
Laibson, David
Meyer, Michelle N.
Lee, James J.
Kong, Augustine
Yengo, Loic
Cesarini, David
Turley, Patrick
Visscher, Peter M.
Beauchamp, Jonathan P.
Benjamin, Daniel J.
Young, Alexander I.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_454389
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_454389
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-022-01016-z
