Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk al...
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles
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Author / Creator
HUNT All-in Headache , International Headache Genetics Consortium , Danish Blood Donor Study Genomic Cohort , Hautakangas, Heidi , Winsvold, Bendik S. , Ruotsalainen, Sanni E. , Bjornsdottir, Gyda , Harder, Aster V. E. , Kogelman, Lisette J. A. , Thomas, Laurent F. , Noordam, Raymond , Benner, Christian , Gormley, Padhraig , Artto, Ville , Banasik, Karina , Bjornsdottir, Anna , Boomsma, Dorret I. , Brumpton, Ben M. , Burgdorf, Kristoffer Sølvsten , Buring, Julie E. , Chalmer, Mona Ameri , de Boer, Irene , Dichgans, Martin , Erikstrup, Christian , Färkkilä, Markus , Garbrielsen, Maiken Elvestad , Ghanbari, Mohsen , Hagen, Knut , Häppölä, Paavo , Hottenga, Jouke-Jan , Hrafnsdottir, Maria G. , Hveem, Kristian , Johnsen, Marianne Bakke , Kähönen, Mika , Kristoffersen, Espen S. , Kurth, Tobias , Lehtimäki, Terho , Lighart, Lannie , Magnusson, Sigurdur H. , Malik, Rainer , Pedersen, Ole Birger , Pelzer, Nadine , Penninx, Brenda W. J. H. , Ran, Caroline , Ridker, Paul M. , Rosendaal, Frits R. , Sigurdardottir, Gudrun R. , Skogholt, Anne Heidi , Sveinsson, Olafur A. , Thorgeirsson, Thorgeir E. , Ullum, Henrik , Vijfhuizen, Lisanne S. , Widén, Elisabeth , van Dijk, Ko Willems , Aromaa, Arpo , Belin, Andrea Carmine , Freilinger, Tobias , Ikram, M. Arfan , Järvelin, Marjo-Riitta , Raitakari, Olli T. , Terwindt, Gisela M. , Kallela, Mikko , Wessman, Maija , Olesen, Jes , Chasman, Daniel I. , Nyholt, Dale R. , Stefánsson, Hreinn , Stefansson, Kari , van den Maagdenberg, Arn M. J. M. , Hansen, Thomas Folkmann , Ripatti, Samuli , Zwart, John-Anker , Palotie, Aarno and Pirinen, Matti
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Migraine affects over a billion individuals worldwide but its genetic underpinning remains largely unknown. Here, we performed a genome-wide association study of 102,084 migraine cases and 771,257 controls and identified 123 loci, of which 86 are previously unknown. These loci provide an opportunity to evaluate shared and distinct genetic component...
Alternative Titles
Full title
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles
Authors, Artists and Contributors
Author / Creator
International Headache Genetics Consortium
Danish Blood Donor Study Genomic Cohort
Hautakangas, Heidi
Winsvold, Bendik S.
Ruotsalainen, Sanni E.
Bjornsdottir, Gyda
Harder, Aster V. E.
Kogelman, Lisette J. A.
Thomas, Laurent F.
Noordam, Raymond
Benner, Christian
Gormley, Padhraig
Artto, Ville
Banasik, Karina
Bjornsdottir, Anna
Boomsma, Dorret I.
Brumpton, Ben M.
Burgdorf, Kristoffer Sølvsten
Buring, Julie E.
Chalmer, Mona Ameri
de Boer, Irene
Dichgans, Martin
Erikstrup, Christian
Färkkilä, Markus
Garbrielsen, Maiken Elvestad
Ghanbari, Mohsen
Hagen, Knut
Häppölä, Paavo
Hottenga, Jouke-Jan
Hrafnsdottir, Maria G.
Hveem, Kristian
Johnsen, Marianne Bakke
Kähönen, Mika
Kristoffersen, Espen S.
Kurth, Tobias
Lehtimäki, Terho
Lighart, Lannie
Magnusson, Sigurdur H.
Malik, Rainer
Pedersen, Ole Birger
Pelzer, Nadine
Penninx, Brenda W. J. H.
Ran, Caroline
Ridker, Paul M.
Rosendaal, Frits R.
Sigurdardottir, Gudrun R.
Skogholt, Anne Heidi
Sveinsson, Olafur A.
Thorgeirsson, Thorgeir E.
Ullum, Henrik
Vijfhuizen, Lisanne S.
Widén, Elisabeth
van Dijk, Ko Willems
Aromaa, Arpo
Belin, Andrea Carmine
Freilinger, Tobias
Ikram, M. Arfan
Järvelin, Marjo-Riitta
Raitakari, Olli T.
Terwindt, Gisela M.
Kallela, Mikko
Wessman, Maija
Olesen, Jes
Chasman, Daniel I.
Nyholt, Dale R.
Stefánsson, Hreinn
Stefansson, Kari
van den Maagdenberg, Arn M. J. M.
Hansen, Thomas Folkmann
Ripatti, Samuli
Zwart, John-Anker
Palotie, Aarno
Pirinen, Matti
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_455741
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_455741
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-021-00990-0
