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The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

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The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_463499

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

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London: Nature Publishing Group UK

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Clonal haematopoiesis, which is highly prevalent in older individuals, arises from somatic mutations that endow a proliferative advantage to haematopoietic cells. Clonal haematopoiesis increases the risk of myocardial infarction and stroke independently of traditional risk factors
1
. Among the common genetic variants that give rise to clonal...

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The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

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Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_463499

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_463499

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ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-021-03341-5

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