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Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease

Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_464167

Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease

About this item

Full title

Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2021-05, Vol.141 (5), p.681-696

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Alzheimer’s disease (AD) is the most prevalent form of dementia and is characterized by abnormal extracellular aggregates of amyloid-β and intraneuronal hyperphosphorylated tau tangles and neuropil threads. Microglia, the tissue-resident macrophages of the central nervous system (CNS), are important for CNS homeostasis and implicated in AD patholog...

Alternative Titles

Full title

Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_464167

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_464167

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-021-02263-w

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