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Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells

Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_466461

Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells

About this item

Full title

Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-11, Vol.10 (1), p.20145, Article 20145

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The secretion of glucagon by pancreatic alpha cells is regulated by a number of external and intrinsic factors. While the electrophysiological processes linking a lowering of glucose concentrations to an increased glucagon release are well characterized, the evidence for the identity and function of the glucose sensor is still incomplete. In the pr...

Alternative Titles

Full title

Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_466461

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_466461

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-76863-z

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