Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise
Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise
About this item
Full title
Author / Creator
Brandão, Bruna B. , Madsen, Søren , Rabiee, Atefeh , Oliverio, Matteo , Ruiz, Gabriel P. , Ferrucci, Danilo L. , Branquinho, Jéssica L. , Razolli, Daniela , Pinto, Silas , Nielsen, Thomas S. , Festuccia, William T. , Martins, Adriano S. , Guerra, Beatriz A. , Knittel, Thiago L. , Søgaard, Ditte , Larsen, Steen , Helge, Jørn W. , Brandauer, Josef , Velloso, Lício A. , Emanuelli, Brice , Kornfeld, Jan-Wilhelm , Kahn, Ronald , Vienberg, Sara G. , Zierath, Juleen R. , Treebak, Jonas T. and Mori, Marcelo A.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
DICER is a key enzyme in microRNA (miRNA) biogenesis. Here we show that aerobic exercise training up-regulates DICER in adipose tissue of mice and humans. This can be mimicked by infusion of serum from exercised mice into sedentary mice and depends on AMPK-mediated signaling in both muscle and adipocytes. Adipocyte DICER is required for whole-body...
Alternative Titles
Full title
Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise
Authors, Artists and Contributors
Author / Creator
Madsen, Søren
Rabiee, Atefeh
Oliverio, Matteo
Ruiz, Gabriel P.
Ferrucci, Danilo L.
Branquinho, Jéssica L.
Razolli, Daniela
Pinto, Silas
Nielsen, Thomas S.
Festuccia, William T.
Martins, Adriano S.
Guerra, Beatriz A.
Knittel, Thiago L.
Søgaard, Ditte
Larsen, Steen
Helge, Jørn W.
Brandauer, Josef
Velloso, Lício A.
Emanuelli, Brice
Kornfeld, Jan-Wilhelm
Kahn, Ronald
Vienberg, Sara G.
Zierath, Juleen R.
Treebak, Jonas T.
Mori, Marcelo A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_468336
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_468336
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2011243117
