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meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and...

meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_470031

meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes

About this item

Full title

meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes

Publisher

London: BioMed Central Ltd

Journal title

Clinical epigenetics, 2020-07, Vol.12 (1), p.1-99, Article 99

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Background Little is known about how genetics and epigenetics interplay in depression. Evidence suggests that genetic variants may change vulnerability to depression by modulating DNA methylation (DNAm) and non-coding RNA (ncRNA) levels. Therefore, the aim of the study was to investigate the effect of the genetic variation, previously identified in...

Alternative Titles

Full title

meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_470031

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_470031

Other Identifiers

ISSN

1868-7075,1868-7083

E-ISSN

1868-7083,1868-7075

DOI

10.1186/s13148-020-00884-8

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