Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis
Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis
About this item
Full title
Author / Creator
Jing, Chenzhi , Castro-Dopico, Tomas , Richoz, Nathan , Tuong, Zewen K. , Ferdinand, John R. , Lok, Laurence S. C. , Loudon, Kevin W. , Banham, Gemma D. , Mathews, Rebeccah J. , Cader, Zaeem , Fitzpatrick, Susan , Bashant, Kathleen R. , Kaplan, Mariana J. , Kaser, Arthur , Johnson, Randall S. , Murphy, Michael P. , Siegel, Richard M. and Clatworthy, Menna R.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
IgG antibodies cause inflammation and organ damage in autoimmune diseases such as systemic lupus erythematosus (SLE). We investigated the metabolic profile of macrophages isolated from inflamed tissues in immune complex (IC)-associated diseases, including SLE and rheumatoid arthritis, and following IgG Fcγ receptor cross-linking. We found that huma...
Alternative Titles
Full title
Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis
Authors, Artists and Contributors
Author / Creator
Castro-Dopico, Tomas
Richoz, Nathan
Tuong, Zewen K.
Ferdinand, John R.
Lok, Laurence S. C.
Loudon, Kevin W.
Banham, Gemma D.
Mathews, Rebeccah J.
Cader, Zaeem
Fitzpatrick, Susan
Bashant, Kathleen R.
Kaplan, Mariana J.
Kaser, Arthur
Johnson, Randall S.
Murphy, Michael P.
Siegel, Richard M.
Clatworthy, Menna R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_470489
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_470489
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2000943117
