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Modeling the transport of nuclear proteins along single skeletal muscle cells

Modeling the transport of nuclear proteins along single skeletal muscle cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_473974

Modeling the transport of nuclear proteins along single skeletal muscle cells

About this item

Full title

Modeling the transport of nuclear proteins along single skeletal muscle cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (6), p.2978-2986

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Skeletal muscle cells contain hundreds of myonuclei within a shared cytoplasm, presenting unique challenges for regulating gene expression. Certain transcriptional programs (e.g., postsynaptic machinery) are segregated to specialized domains, while others (e.g., contractile proteins) do not show spatial confinement. Furthermore, local stimuli, such...

Alternative Titles

Full title

Modeling the transport of nuclear proteins along single skeletal muscle cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_473974

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_473974

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1919600117

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