Frequencies of clinically important CYP2C19 and CYP2D6 alleles are graded across Europe
Frequencies of clinically important CYP2C19 and CYP2D6 alleles are graded across Europe
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Publisher
England: Nature Publishing Group
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English
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England: Nature Publishing Group
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Contents
CYP2C19 and CYP2D6 are important drug-metabolizing enzymes that are involved in the metabolism of around 30% of all medications. Importantly, the corresponding genes are highly polymorphic and these genetic differences contribute to interindividual and interethnic differences in drug pharmacokinetics, response, and toxicity. In this study we system...
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Full title
Frequencies of clinically important CYP2C19 and CYP2D6 alleles are graded across Europe
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TN_cdi_swepub_primary_oai_swepub_ki_se_478056
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_478056
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ISSN
1018-4813
E-ISSN
1476-5438
DOI
10.1038/s41431-019-0480-8
