Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab i...
Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial
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Author / Creator
Rozeman, Elisa A, MD , Menzies, Alexander M, MD , van Akkooi, Alexander C J, MD , Adhikari, Chandra, MD , Bierman, Carolien, BSc , van de Wiel, Bart A, MD , Scolyer, Richard A, Prof , Krijgsman, Oscar, PhD , Sikorska, Karolina, PhD , Eriksson, Hanna, MD , Broeks, Annegien, PhD , van Thienen, Johannes V, MD , Guminski, Alexander D, MD , Acosta, Alex Torres, MA , ter Meulen, Sylvia, CNS , Koenen, Anne Miek, CNS , Bosch, Linda J W, PhD , Shannon, Kerwin, MD , Pronk, Loes M, MSc , Gonzalez, Maria, MSc , Ch'ng, Sydney, MD , Grijpink-Ongering, Lindsay G, BSc , Stretch, Jonathan, MD , Heijmink, Stijn, MD , van Tinteren, Harm, PhD , Haanen, John B A G, Prof , Nieweg, Omgo E, Prof , Klop, Willem M C, MD , Zuur, Charlotte L, MD , Saw, Robyn P M, MD , van Houdt, Winan J, MD , Peeper, Daniel S, Prof , Spillane, Andrew J, Prof , Hansson, Johan, MD , Schumacher, Ton N, Prof , Long, Georgina V, Prof and Blank, Christian U, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
SummaryBackgroundThe outcome of patients with macroscopic stage III melanoma is poor. Neoadjuvant treatment with ipilimumab plus nivolumab at the standard dosing schedule induced pathological responses in a high proportion of patients in two small independent early-phase trials, and no patients with a pathological response have relapsed after a med...
Alternative Titles
Full title
Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial
Authors, Artists and Contributors
Author / Creator
Menzies, Alexander M, MD
van Akkooi, Alexander C J, MD
Adhikari, Chandra, MD
Bierman, Carolien, BSc
van de Wiel, Bart A, MD
Scolyer, Richard A, Prof
Krijgsman, Oscar, PhD
Sikorska, Karolina, PhD
Eriksson, Hanna, MD
Broeks, Annegien, PhD
van Thienen, Johannes V, MD
Guminski, Alexander D, MD
Acosta, Alex Torres, MA
ter Meulen, Sylvia, CNS
Koenen, Anne Miek, CNS
Bosch, Linda J W, PhD
Shannon, Kerwin, MD
Pronk, Loes M, MSc
Gonzalez, Maria, MSc
Ch'ng, Sydney, MD
Grijpink-Ongering, Lindsay G, BSc
Stretch, Jonathan, MD
Heijmink, Stijn, MD
van Tinteren, Harm, PhD
Haanen, John B A G, Prof
Nieweg, Omgo E, Prof
Klop, Willem M C, MD
Zuur, Charlotte L, MD
Saw, Robyn P M, MD
van Houdt, Winan J, MD
Peeper, Daniel S, Prof
Spillane, Andrew J, Prof
Hansson, Johan, MD
Schumacher, Ton N, Prof
Long, Georgina V, Prof
Blank, Christian U, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_479368
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_479368
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(19)30151-2
