Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ame...
Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity
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Author / Creator
Huang, Zhenxing , Wang, Jianhe , Xu, Xiaoli , Wang, Haishan , Qiao, Yuan , Chu, Wern Cui , Xu, Shengli , Chai, Louis , Cottier, Fabien , Pavelka, Norman , Oosting, Marije , Joosten, Leo A. B. , Netea, Mihai , Ng, Carol Yee Leng , Leong, Khai Pang , Kundu, Parag , Lam, Kong-Peng , Pettersson, Sven and Wang, Yue
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The human microbiota provides tonic signals that calibrate the host immune response
1
,
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, but their identity is unknown. Bacterial peptidoglycan (PGN) subunits are likely candidates since they are well-known immunity-enhancing adjuvants, released by most bacteria during growth, and have been found in the blood of healthy people
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Alternative Titles
Full title
Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_481505
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_481505
Other Identifiers
ISSN
2058-5276
E-ISSN
2058-5276
DOI
10.1038/s41564-019-0381-1
