Claudin-3-deficient C57BL/6J mice display intact brain barriers
Claudin-3-deficient C57BL/6J mice display intact brain barriers
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Author / Creator
Castro Dias, Mariana , Coisne, Caroline , Lazarevic, Ivana , Baden, Pascale , Hata, Masaki , Iwamoto, Noriko , Francisco, David Miguel Ferreira , Vanlandewijck, Michael , He, Liqun , Baier, Felix A. , Stroka, Deborah , Bruggmann, Rémy , Lyck, Ruth , Enzmann, Gaby , Deutsch, Urban , Betsholtz, Christer , Furuse, Mikio , Tsukita, Shoichiro and Engelhardt, Britta
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The tight junction protein claudin-3 has been identified as a transcriptional target of the Wnt/β-catenin signaling pathway regulating blood-brain barrier (BBB) maturation. In neurological disorders loss of claudin-3 immunostaining is observed at the compromised BBB and blood-cerebrospinal fluid barrier (BCSFB). Although these observations support...
Alternative Titles
Full title
Claudin-3-deficient C57BL/6J mice display intact brain barriers
Authors, Artists and Contributors
Author / Creator
Coisne, Caroline
Lazarevic, Ivana
Baden, Pascale
Hata, Masaki
Iwamoto, Noriko
Francisco, David Miguel Ferreira
Vanlandewijck, Michael
He, Liqun
Baier, Felix A.
Stroka, Deborah
Bruggmann, Rémy
Lyck, Ruth
Enzmann, Gaby
Deutsch, Urban
Betsholtz, Christer
Furuse, Mikio
Tsukita, Shoichiro
Engelhardt, Britta
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_482687
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_482687
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-36731-3