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Claudin-3-deficient C57BL/6J mice display intact brain barriers

Claudin-3-deficient C57BL/6J mice display intact brain barriers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_482687

Claudin-3-deficient C57BL/6J mice display intact brain barriers

About this item

Full title

Claudin-3-deficient C57BL/6J mice display intact brain barriers

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-01, Vol.9 (1), p.203, Article 203

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The tight junction protein claudin-3 has been identified as a transcriptional target of the Wnt/β-catenin signaling pathway regulating blood-brain barrier (BBB) maturation. In neurological disorders loss of claudin-3 immunostaining is observed at the compromised BBB and blood-cerebrospinal fluid barrier (BCSFB). Although these observations support...

Alternative Titles

Full title

Claudin-3-deficient C57BL/6J mice display intact brain barriers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_482687

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_482687

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-36731-3