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NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_485534

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

About this item

Full title

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2018-10, Vol.19 (10), p.1083-1092

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The activation of natural killer (NK) cells depends on a change in the balance of signals from inhibitory and activating receptors. The activation threshold values of NK cells are thought to be set by engagement of inhibitory receptors during development. Here, we found that the activating receptor NKG2D specifically set the activation threshold fo...

Alternative Titles

Full title

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_485534

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_485534

Other Identifiers

ISSN

1529-2908,1529-2916

E-ISSN

1529-2916

DOI

10.1038/s41590-018-0209-9

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