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Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dy...

Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_487338

Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dysregulation in major depression

About this item

Full title

Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dysregulation in major depression

Publisher

England: Nature Publishing Group

Journal title

Neuropsychopharmacology (New York, N.Y.), 2018-09, Vol.43 (10), p.2134-2145

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

An enhanced understanding of the pathophysiology of depression would facilitate the discovery of new efficacious medications. To this end, we examined hippocampal transcriptional changes in rat models of disease and in humans to identify common disease signatures by using a new algorithm for signature-based clustering of expression profiles. The to...

Alternative Titles

Full title

Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dysregulation in major depression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_487338

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_487338

Other Identifiers

ISSN

0893-133X

E-ISSN

1740-634X

DOI

10.1038/s41386-018-0117-6

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