Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory genera...
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
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Utsugisawa, Kimiaki , Kissel, John T , O'Brien, Fanny , Lamont, Phillipa , Roberts, Leslie , De Mey, Katrien , Tilkin, Petra , Alves de Siqueira Carvalho, Alzira , Paiva, Gabriel , Prando, Natalia , Souza, Iandra , Campbell, Natasha , Blackmore, Derrick , Autzen, Anne Mette , Harrison, Tuula , Moutarde, Julie , Le Masson, Gwendal , Wilson, Amy , Fricke, Karin , Horvath, Melinda , Matolcsi, Judit , Szabadosne, Brigitta , Vecsei, Laszlo , Konyane, Monika , Troili, Fernanda , Di Pasquale, Antonella , Filla, Alessandro , Campanella, Angela , Inghilleri, Maurizio , Fionda, Laura , Gabriele, Maria , Salvatore Caramma, Andrea , Kanzaki, Akiko , Jingu, Maki , Yoshimura, Shunsuke , Kobashikawa, Tomomi , Yamashita, Yumi , Kawamura, Tomohiro , Higuchi, Eriko , Osakada, Kaori , Hisahara, Shin , Suzuki, Shuichiro , Ogasawara, Junichi , Shinozaki, Hirokazu , Gibson, Tamar , Keijzers, Maria Johanna , Kim, Byung-Jo , Ra, HyeJin , Kim, Byoung Joon , Lee, JiEun , Kim, Seung Min , Kim, Yool-hee , Lee, Hyung Seok , Yarmoschuk, Asya , Nesterova, Yulia , Fernandez-Fournier, Mireya , Hietala, Albert , Andersson, Blanka , Boz, Cavit , Erdem-Ozdamar, Sevim , Terzi, Murat , Gollogly, Jakit , Smalley, Nicole , Silvestri, Nicholas , Loor, John , Pascuzzi, Robert , Snook, Riley , Carter, Cynthia , Levine-Weinberg, Mark , Simpson, Ericka , Kaur, Harpreet , Crabtree, Brigid , Taber, Sandra , Gilchrist, James , Darnell, Taylor , Goyal, Neelam , Sakamuri, Sarada , Jones, Floyd , Alsharabati, Mohammad , Butters, Janelle , Goyal, Namita , Garcia, Sonia , Echevarria, Laura , Pulley, Michael , Shabbir, Yasmeen , Gutmann, Laurie , Gutmann, Ludwig , Hafer-Macko, Charlene , Chopra, Manisha , Kaufman, Jacob , McClain, Terry , Harvey, Brittany , Huynh, Kristin , Droker, Brian , Weiss, Michael , Downing, Sharon , Bernitsas, Evanthia , Kumar Sriwastava, Shitiz , Jia, Kelly , Patwa, Huned and REGAIN Study Group
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Complement is likely to have a role in refractory generalised myasthenia gravis, but no approved therapies specifically target this system. Results from a phase 2 study suggested that eculizumab, a terminal complement inhibitor, produced clinically meaningful improvements in patients with anti-acetylcholine receptor antibody-positive refractory gen...
Alternative Titles
Full title
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
Authors, Artists and Contributors
Author / Creator
Kissel, John T
O'Brien, Fanny
Lamont, Phillipa
Roberts, Leslie
De Mey, Katrien
Tilkin, Petra
Alves de Siqueira Carvalho, Alzira
Paiva, Gabriel
Prando, Natalia
Souza, Iandra
Campbell, Natasha
Blackmore, Derrick
Autzen, Anne Mette
Harrison, Tuula
Moutarde, Julie
Le Masson, Gwendal
Wilson, Amy
Fricke, Karin
Horvath, Melinda
Matolcsi, Judit
Szabadosne, Brigitta
Vecsei, Laszlo
Konyane, Monika
Troili, Fernanda
Di Pasquale, Antonella
Filla, Alessandro
Campanella, Angela
Inghilleri, Maurizio
Fionda, Laura
Gabriele, Maria
Salvatore Caramma, Andrea
Kanzaki, Akiko
Jingu, Maki
Yoshimura, Shunsuke
Kobashikawa, Tomomi
Yamashita, Yumi
Kawamura, Tomohiro
Higuchi, Eriko
Osakada, Kaori
Hisahara, Shin
Suzuki, Shuichiro
Ogasawara, Junichi
Shinozaki, Hirokazu
Gibson, Tamar
Keijzers, Maria Johanna
Kim, Byung-Jo
Ra, HyeJin
Kim, Byoung Joon
Lee, JiEun
Kim, Seung Min
Kim, Yool-hee
Lee, Hyung Seok
Yarmoschuk, Asya
Nesterova, Yulia
Fernandez-Fournier, Mireya
Hietala, Albert
Andersson, Blanka
Boz, Cavit
Erdem-Ozdamar, Sevim
Terzi, Murat
Gollogly, Jakit
Smalley, Nicole
Silvestri, Nicholas
Loor, John
Pascuzzi, Robert
Snook, Riley
Carter, Cynthia
Levine-Weinberg, Mark
Simpson, Ericka
Kaur, Harpreet
Crabtree, Brigid
Taber, Sandra
Gilchrist, James
Darnell, Taylor
Goyal, Neelam
Sakamuri, Sarada
Jones, Floyd
Alsharabati, Mohammad
Butters, Janelle
Goyal, Namita
Garcia, Sonia
Echevarria, Laura
Pulley, Michael
Shabbir, Yasmeen
Gutmann, Laurie
Gutmann, Ludwig
Hafer-Macko, Charlene
Chopra, Manisha
Kaufman, Jacob
McClain, Terry
Harvey, Brittany
Huynh, Kristin
Droker, Brian
Weiss, Michael
Downing, Sharon
Bernitsas, Evanthia
Kumar Sriwastava, Shitiz
Jia, Kelly
Patwa, Huned
REGAIN Study Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_493112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_493112
Other Identifiers
ISSN
1474-4422
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(17)30369-1
