Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients...
Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients with Schizophrenia: A Retrospective Observational Study
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Background
Clozapine is restricted to use in patients with treatment-refractory schizophrenia due to the risk of a serious drop in absolute neutrophil granulocyte count (ANC). The formation of reactive, unstable metabolites (adducts) has been suggested as a mechanism of clozapine-induced granulocyte decline. These adducts are not detectable in v...
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Full title
Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients with Schizophrenia: A Retrospective Observational Study
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TN_cdi_swepub_primary_oai_swepub_ki_se_493808
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_493808
Other Identifiers
ISSN
1172-7047
E-ISSN
1179-1934
DOI
10.1007/s40263-017-0469-1
