Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Huma...
Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells
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Publisher
United States: American Thoracic Society
Journal title
Language
English
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Publisher
United States: American Thoracic Society
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Scope and Contents
Contents
Type 2-associated goblet cell hyperplasia and mucus hypersecretion are well known features of asthma. 15-Lipoxygenase-1 (15LO1) is induced by the type 2 cytokine IL-13 in human airway epithelial cells (HAECs) in vitro and is increased in fresh asthmatic HAECs ex vivo. 15LO1 generates a variety of products, including 15-hydroxyeicosatetraenoic acid...
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Full title
Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_495329
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_495329
Other Identifiers
ISSN
1044-1549
E-ISSN
1535-4989
DOI
10.1165/rcmb.2017-0031OC
