Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to...
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor
About this item
Full title
Author / Creator
Litchfield, Kevin , Levy, Max , Orlando, Giulia , Loveday, Chey , Law, Philip J , Migliorini, Gabriele , Holroyd, Amy , Broderick, Peter , Karlsson, Robert , Haugen, Trine B , Kristiansen, Wenche , Nsengimana, Jérémie , Fenwick, Kerry , Assiotis, Ioannis , Kote-Jarai, ZSofia , Dunning, Alison M , Muir, Kenneth , Peto, Julian , Eeles, Rosalind , Easton, Douglas F , Dudakia, Darshna , Orr, Nick , Pashayan, Nora , Bishop, D Timothy , Reid, Alison , Huddart, Robert A , Shipley, Janet , Grotmol, Tom , Wiklund, Fredrik , Houlston, Richard S , Turnbull, Clare , The PRACTICAL Consortium , UK Testicular Cancer Collaboration and PRACTICAL Consortium
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Clare Turnbull and colleagues report discovery of 19 new susceptibility loci for testicular germ cell tumor (TGCT) and provide evidence for a network of physical interactions between TGCT risk variants and candidate causal genes. Their findings implicate widespread disruption of developmental transcriptional regulators in TGCT susceptibility, consi...
Alternative Titles
Full title
Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor
Authors, Artists and Contributors
Author / Creator
Levy, Max
Orlando, Giulia
Loveday, Chey
Law, Philip J
Migliorini, Gabriele
Holroyd, Amy
Broderick, Peter
Karlsson, Robert
Haugen, Trine B
Kristiansen, Wenche
Nsengimana, Jérémie
Fenwick, Kerry
Assiotis, Ioannis
Kote-Jarai, ZSofia
Dunning, Alison M
Muir, Kenneth
Peto, Julian
Eeles, Rosalind
Easton, Douglas F
Dudakia, Darshna
Orr, Nick
Pashayan, Nora
Bishop, D Timothy
Reid, Alison
Huddart, Robert A
Shipley, Janet
Grotmol, Tom
Wiklund, Fredrik
Houlston, Richard S
Turnbull, Clare
The PRACTICAL Consortium
UK Testicular Cancer Collaboration
PRACTICAL Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_496165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_496165
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/ng.3896
