Genome-wide association analysis identifies novel blood pressure loci and offers biological insights...
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
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The CHD Exome+ Consortium , The International Consortium of Blood Pressure (ICBP) 1000G Analyses , The International Genomics of Blood Pressure (iGEN-BP) Consortium , The UK Biobank CardioMetabolic Consortium BP working group , The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium , The GoT2DGenes Consortium , The ExomeBP Consortium , The T2D-GENES Consortium , International Consortium of Blood Pressure (ICBP) 1000G Analyses , Understanding Society Scientific group , CHD Exome+ Consortium , Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium , International Genomics of Blood Pressure (iGEN-BP) Consortium , Lifelines Cohort Study , BIOS Consortium , UK Biobank CardioMetabolic Consortium BP working group , ExomeBP Consortium , GoT2DGenes Consortium , T2D-GENES Consortium , Warren, Helen R , Evangelou, Evangelos , Cabrera, Claudia P , Gao, He , Ren, Meixia , Mifsud, Borbala , Ntalla, Ioanna , Surendran, Praveen , Liu, Chunyu , Cook, James P , Kraja, Aldi T , Drenos, Fotios , Loh, Marie , Verweij, Niek , Marten, Jonathan , Karaman, Ibrahim , Lepe, Marcelo P Segura , O'Reilly, Paul F , Knight, Joanne , Snieder, Harold , Kato, Norihiro , He, Jiang , Tai, E Shyong , Said, M Abdullah , Porteous, David , Alver, Maris , Poulter, Neil , Farrall, Martin , Gansevoort, Ron T , Padmanabhan, Sandosh , Mägi, Reedik , Stanton, Alice , Connell, John , Bakker, Stephan J L , Metspalu, Andres , Shields, Denis C , Thom, Simon , Brown, Morris , Sever, Peter , Esko, Tõnu , Hayward, Caroline , van der Harst, Pim , Saleheen, Danish , Chowdhury, Rajiv , Chambers, John C , Chasman, Daniel I , Chakravarti, Aravinda , Newton-Cheh, Christopher , Lindgren, Cecilia M , Levy, Daniel , Kooner, Jaspal S , Keavney, Bernard , Tomaszewski, Maciej , Samani, Nilesh J , Howson, Joanna M M , Tobin, Martin D , Munroe, Patricia B , Ehret, Georg B and Wain, Louise V
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Mark Caulfield, Paul Elliott and colleagues use data from the UK Biobank to perform genome-wide association analysis for blood pressure traits. They identify and validate 107 novel loci and highlight new biological pathways for potential therapeutic intervention for hypertension.
Elevated blood pressure is the leading heritable risk factor for c...
Alternative Titles
Full title
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
Authors, Artists and Contributors
Author / Creator
The International Consortium of Blood Pressure (ICBP) 1000G Analyses
The International Genomics of Blood Pressure (iGEN-BP) Consortium
The UK Biobank CardioMetabolic Consortium BP working group
The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium
The GoT2DGenes Consortium
The ExomeBP Consortium
The T2D-GENES Consortium
International Consortium of Blood Pressure (ICBP) 1000G Analyses
Understanding Society Scientific group
CHD Exome+ Consortium
Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium
International Genomics of Blood Pressure (iGEN-BP) Consortium
Lifelines Cohort Study
BIOS Consortium
UK Biobank CardioMetabolic Consortium BP working group
ExomeBP Consortium
GoT2DGenes Consortium
T2D-GENES Consortium
Warren, Helen R
Evangelou, Evangelos
Cabrera, Claudia P
Gao, He
Ren, Meixia
Mifsud, Borbala
Ntalla, Ioanna
Surendran, Praveen
Liu, Chunyu
Cook, James P
Kraja, Aldi T
Drenos, Fotios
Loh, Marie
Verweij, Niek
Marten, Jonathan
Karaman, Ibrahim
Lepe, Marcelo P Segura
O'Reilly, Paul F
Knight, Joanne
Snieder, Harold
Kato, Norihiro
He, Jiang
Tai, E Shyong
Said, M Abdullah
Porteous, David
Alver, Maris
Poulter, Neil
Farrall, Martin
Gansevoort, Ron T
Padmanabhan, Sandosh
Mägi, Reedik
Stanton, Alice
Connell, John
Bakker, Stephan J L
Metspalu, Andres
Shields, Denis C
Thom, Simon
Brown, Morris
Sever, Peter
Esko, Tõnu
Hayward, Caroline
van der Harst, Pim
Saleheen, Danish
Chowdhury, Rajiv
Chambers, John C
Chasman, Daniel I
Chakravarti, Aravinda
Newton-Cheh, Christopher
Lindgren, Cecilia M
Levy, Daniel
Kooner, Jaspal S
Keavney, Bernard
Tomaszewski, Maciej
Samani, Nilesh J
Howson, Joanna M M
Tobin, Martin D
Munroe, Patricia B
Ehret, Georg B
Wain, Louise V
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_499431
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_499431
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/ng.3768
