Speedy A–Cdk2 binding mediates initial telomere–nuclear envelope attachment during meiotic prophase...
Speedy A–Cdk2 binding mediates initial telomere–nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation
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Author / Creator
Tu, Zhaowei , Bayazit, Mustafa Bilal , Liu, Hongbin , Zhang, Jingjing , Busayavalasa, Kiran , Risal, Sanjiv , Shao, Jingchen , Satyanarayana, Ande , Coppola, Vincenzo , Tessarollo, Lino , Singh, Meenakshi , Zheng, Chunwei , Han, Chunsheng , Chen, Zijiang , Kaldis, Philipp , Gustafsson, Jan-Åke and Liu, Kui
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Telomere attachment to the nuclear envelope (NE) is a prerequisite for chromosome movement during meiotic prophase I that is required for pairing of homologous chromosomes, synapsis, and homologous recombination. Here we show that Speedy A, a noncanonical activator of cyclin-dependent kinases (Cdks), is specifically localized to telomeres in propha...
Alternative Titles
Full title
Speedy A–Cdk2 binding mediates initial telomere–nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_500088
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_500088
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1618465114
